Old bash.org comment:

Person 1: you know what sucks?

Person 2: vacuums?

Person 1 [another query I can recall]

Person 2: black holes?

Person 1: you know what’s just not cool?

Person 2: volcanoes?

Person 1: sigh

edit: Just remembered that the second query was “you know what sucks in a metaphorical sense?”

You know what’s cool about women? While I’m no expert, they seem to be basically men with different hills and valleys … And admittedly societal expectations.

Do you know when women are into you?

Literally (part of) the plot of the Red Rising series.